I added some insulation on the inside firewall by the driver's feet for a noticeable improvement
Also the Door steps and doors them selves are a big source of road noise. Dynamat type products in the door panels on the metal skin and something on the door panel, or inside the door panel will help.
I never noticed any improvement after liberal application of rubberized undercoating in the wheel wells and other areas under the body. I really tried to believe this particular effort made a difference, but could not convince myself.
I made some thick wheel well skirts as when my original one disintegrated and when fully removed I noticed a lot more reflected engine noise.


These wheel well skirts might have effected aerodynamics, as it seems that when driving in the rain, with a waxed windshield, the speed at which the rain drops cruise up and over the windshield needs to be higher. I cannot swear to this effect and will not be removing the skirts to test. It was something I noticed the first time I drove in the rain after installment.
The longer thicker skirts reduced reflected engine noise, and highway/tire noise was lessened to a noticeable degree as well.
Certain tires will make lots more noise than others, and some that were quiet when new will be much louder with half their tread left.
My tires are kind of aggressive AT tires, but most noise at Highway speeds is wind related on my Dodge, and I'm hoping a future smoother transition between windshield and fiberglass roof, as well as the window vent visors will reduce wind noise at highway speeds.