I have ScanGauge in my pickup and car trip computer on our wagon.
I make comparison how much saved trip time cost me in fuel.
For example wagon at 65 mph makes 26 mpg. At 80 it makes 22mpg.
I calculated that on our routine 550 miles trip to Vegas going faster will give me additional 1 hr of vacations for $7 in fuel cost. Since our vacations cost us average $50 for each active hr, gaining 1 hr extra for $7 is good deal.
On my pickup going from 70 to 80 mph on the trip would cost me well over $50 in fuel cost, so I drive slower.
In motorhome you have more factors. While driving heavy set, you might notice that for example at 60 mph the transmission will have to downshift on lot of grades, what is killing economy pretty bad.
Going at 65 mph will make grades without downshifting.
So minimally lower economy on flat land can turn fuel savings on hilly highway.
Rule of thumb is that the best rpm for cruising are those between max torque and max HP