When I switched to Yokohama tires on our E450 Sunseeker 2300, I had to deflate the tires significantly from the door sticker. After perusing tire pressure charts (Yokohama doesn't have one for my tire that I can find) based on my loaded weight, I'm now over-pressure at 50 psi in front and 65 in the rear. The charts call for 45 front and 60 rear for my loaded weight.
I have very limited experience with this tire pressure other than our recent 4000 mile trip towing our Jeep Wrangler. Passing trucks and cross winds have a greatly reduced effect. Grooves, dips, and truck wear in the lanes don't throw the RV around anymore, and unless I see unusual wear, I plan on sticking with this pressure.
YMMV!