Know your weight. If you want to plan for a bit more weight that's fine but don't exceed the gross rating (it's not just an arbitrary number) Use the tables/charts to know the pressure for your brand/size. The pressure is when tires are cold, the increase from running down the road should not be a concern. The pressure build up from running is caused by heat increase from tire flex and don't try to outguess the engineers on that. One questionable statement I often see is where people think that going up a load range in tires will allow them to use lower pressures and get a softer ride...just doing that based on tables can be dangerous. There are tires that need minimum pressures to safely stay on the rims and running pressures at the very bottom of the tables can cause flexing that raises some pretty high heat which is asking for big trouble.