Never been a fan of crates...so that's one option not open to me. My dog loves my pickup. Also like wifes' car. But the motorhome? Forget it. Clearly uncomfortable, with shaking (an incredible vibration) and drooling somewhat, we only have two theory's:
1- the sound (frequency) of the engine (a V-10)
2- the first time she got in the motorhome, she said to herself : Ah! a new house! but then the house moved.
We won't go the "medication" route,, but we have no idea what to do to calm her anxiety down. She's only 3....hopefully as she ages she'll calm a bit. Don't know.