Our 12 year old Golden Retriever has had recurrent bouts of reactive histiocytosis over the past six or seven years. The go to drug in the past has been doxycycline, and it was always effective...until this time. (The doxy has also gone from $35 for a 30 day supply to $400, which is highway robbery for a generic drug.)
After a month on the doxy and having more and more bumps that got larger and larger, our canine dermatologist put Gus on Atopica. It only took five days to show marked improvement and in less than three weeks the lesions were totally gone. We saw the doctor yesterday, and she has cut the dosage from once a day to once every other day for the next 30 days. If he does well on that, she will cut the dosage even further until we find the minimum dose that will be effective.
For Gus it was a miracle drug.