Thanks for the quick replies!
Yes we do have space reserved at Bridge Bay. I like the Tower/Roosevelt and Norris areas better, but BB is where I could confirm space. I've been to YNP a few times before, most recently about 15 years ago, but only in a SUV. This will be a different experience altogether.
We pick up our rental in Denver, so I'm afraid that's the one must of the whole trip. I've driven I 70 a dozen times or more, but never taken US 40. A quick map recon of CO 14 looks like it has as many wiggles as US 40, but its hard to judge the degree of difficulty on the scale I'm using.
My wife and I loved Tetons the last time we were there, so that's already on the list. I flew into Jackson this winter, we saw a Moose with calf on the airport access road.
What do you mean by 'dry camp'? Is that parking without water and power hookups? I assumed we would be on our own the whole time. But that begs the question, what is the endurance of a black water tank (13 gallons?), in days, for a family of 4? My wife is never a fan of pit latrines, and the later it gets in the season, the more I am inclined to agree with her.
We plan to stock up on consumables for the trip in Denver, so hopefully we won't need much in the way of supplies once we're on our way!