Now for comments pertaining to the question at hand.
If you want or need a pickup truck, now is the perfect excuse to get one. But you need to be comfortable towing a large trailer through the mountains and windy weather. Not for everyone.
If you get a C, I would not do it without a toad, but that could open up some great adventures if you had a little Jeep or something you could get 4 wheel with. Although I've taken a full size truck over a lot of "jeep trails" in the mtns.
My only experience with a C is friends rented one last year visiting us in AK. I could take my truck/camper a lot of places the C wouldn't go, if you'll be getting off the beaten path. Kids loved the C and we let them move around in it when on the road, slow AK back roads. It would have been near impossible to get them to sit strapped in at the kitchen table for hours at a time. They liked the house on wheels. I'd prefer to not have that argument with the kids every half hour.
This is a good question as every RV is a trade off. Truck campers too. They are way expensive for how much room you get if you want a spacious rv and you'll need a big @ss truck for any decent size TC where you can tow a fair size TT with a stout newer 1/2 ton.
A C is going to be a super pooch and even worse mileage if you're pulling a toad than if you get a newer pickup with 350-400hp and a reasonable TC.
If I was deciding between the 2 today, I'd go truck and TC hands down, but I'm comfortable pulling about anything anywhere.
