Look at the Tach run it uphill at just below redline or lower if pulling is EZer, down shift to a gear on the uphill to keep the V-8 or V-10 spining RPM to keep cooling to a max. Down hill shift to a lower gear or same gear coming up. Once you down shift manually you will be in Tow Haul mode OR in the olden days overdrive. Keep at or just below red line as needed for compression braking. If speed or RPM rise too high stab brake(brake firmly) to 5 MPH below desired RPM or speed then let brakes cool, repeat as needed. Picking the correct gear going down hill with the E450 31' and 4-runner in tow I very seldom need the brakes. Only experience can tell. Also find just keeping with the trucks(most have been there before) will keep you out of trouble untill you have a few mountain pass's behind you.
LEN