Another question to ask is how much space do you really need to feel comfortable living in? By living overseas for many years, we learned that a few hundred square ft. were enough if we didn't carry a lot of "junque".
If you can be satisfied in the equivalent of a studio apartment, then either a small travel trailer -- Casita, etc. -- and a decent towing vehicle, or a short (26' or less) Class C or B+ MH might be all you need. Just 10 minutes to drop your TT or hookups at the campsite and you can explore in the MH or towing vehicle.
If you want the space of a full apartment, then a smaller (30' or less) Class A and a 4 wheels down towable vehicle would work.
But, the mechanics of hitching a large TT or 5th wheel are more than I'd like do solo (even with a proper hitch camera). And, parking a large Class A isn't a task I'd choose to do solo, either.
The other tasks of RV operation -- water, sewer and power hookups; tank dumps; etc. -- are quickly learned. There are also a number of handy hacks to make it easier on a solo, such as quick disconnects on water hoses, SmartPlug power cables and Power Management systems (more than a mere surge protector), and tank flushers & macerator pumps to simplify the dreaded dumps.
I did most of our routine operations solo, due to DW's disability, but we built our coach so that she could do any of them she chose to -- except driving. Most of the time, she just chose not to! ;}
