If I had a vented compartment that would hold four flooded lead acid type batteries they would be 6v industrial true deep cycle ones. If one cell in one battery failed I would disconnect it and its partner battery from the bank and still have the 12v needed for the RV electronics (fridge, water pump, furnace control, lights). I could then wait until it was convenient to get the bad battery replaced or might decide to replace two or all four batteries.
With only two batteries and use out on the open road the better choice is two matched 12v batteries.
A common mistake made is to compare a FLAT battery performance and cost and longevity with an AGM battery. For RV use the AGM is not likely to last as long and it will cost twice as much up front.
FLAT batteries will handle partial discharge and partial recharge cycles better than AGM type batteries and this contributes to their longer life when used in an RV.
Less than 6v batteries in auto group sizes and larger are made to keep the weight of the battery manageable by the average human without need for a forklift or a hoist. Insustrial batteries come in voltage outputs as low as 2v and are commonly used for data centers, phone company switch installations, and cell towers.