As a kid in the 1970's my parents had a 24 foot travel trailer we used for camping/fishing in the Wyoming mountains. Fast forward forty years and I purchased a 32 foot travel trailer to use as my "home" during a temporary project assignment and then have as a family toy. Just two years ago as young grandchildren started appearing, my wife and I upgraded to a 39 foot diesel pusher motorhome towing a Jeep Wrangler. The point of all of this, whether owning a travel trailer, fifth wheel or motorhome, we non-truck camper RV owners are always hooking/un-hooking whatever we tow. That's just part of RV life!
When my wife and I upgraded to a motorhome, we found a very nice, gently used (only 6,000 miles) 2007 model for less than the cost of a new/one year old fifth wheel trailer. And we didn't have to also spend $50,00-$60,000 for a new 3/4 ton/one ton truck to pull a fifth wheel. My motorhome has several "push button" set-up conveniences over the travel trailer I owned. When boon-docking (such as an LSU football game) I don't have to set up parallel Honda 2000 generator with five gallon feed tank, hand crank leveling jacks, have very restricted use of fresh water, etc.
Fifth wheel trailers from my point of view have the best set-ups for long term living as they often come with a large, comfortably furnished "living room".
It boils down to what you want to do with an RV. Travel trailers are the most economic and are arranged for short term living. Fifth wheel trailers (and the truck needed to tow them) are expensive a very well suited for long term living. New motorhomes are the most expensive (unless you're lucky like I was to find a gently used motorhome) but motorhomes have the most conveniences.
Hope this gives you some thoughts to ponder.