While snowbirding, we frequently meet folks who have a fifth and large pickup truck, and a chaser. They make one big trip from north to south, and back, every year, then benefit from having a small, maneuverable car to use for the entire winter. Not ideal, but doable. As for more frequent trips using a chaser, sorry but I think it's a ridiculous idea. Nothing but a PITA.
We once camped next to about the silliest example of this whole deal I have seen, in two decades, and 200K+ miles of travel. A couple, full timing in a large fifth, a pickup, a medium sized SUV and a medium sized cargo trailer behind. They literally have their own parade when they hit the road. Two drivers, four vehicles, fourteen tires on the road.