Let's see... While towing: Had to emergency stop for a fallen large recliner (big heavily padded sort) on the Schuylkill Expressway in heavy fast-moving traffic once. Couple encounters with deer, once swerved as there was no traffic, another time stopped. Got forced sideways into a construction barrier when someone decided to merge into my lane without making sure it was clear, and didn't stop doing it quickly enough after I honked.
The former cases all went fine - no issues with trailer and didn't hit anything. The last case resulted in some minor scrapes and a lost mirror.