My Ford F-150 is Flex-Fuel, so the ECM knows that there is booze in the tank and adjusts the fuel/air ratio accordingly. It seems to add a couple more horses when towing, but that is because alcohol burns hotter (why it is used in race cars), but needs more of it.
Of course, MPG goes through the floor, so E-85 is more expensive overall.
When looking at motorhomes, newer Ford models have a note on them stating that even though the engine can handle E-85... the generator can't, so don't run the Onan if one is using ethanol.
I still remember when "gasahol" was introduced in the US in the late 1970s/early 1980s. It managed to completely destroy the engine on a family member's 1978 Honda Accord (the second that was bought in Austin) within less than a mile. Apparently the gas station did not mark that they were using ethanol blends.
