E350 - Does this make any sense?
We have have had class B/small class C motorhomes for about 15 years. Our current unit is a 2006 Phoenix Cruiser 2100 (21ft) on an E350 with dual rear wheels. With the V10 (6.8L)it is rated at 18,500l...
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I think you'll also be fine, provided you are diligent with LOADED trailer weights, and you use a good weight distribution hitch. You will likely need to upgrade the RV's hitch receiver to one compatible with weight distribution (most RV ones are not). The regular E350 van receivers fit simply by re-arranging the frame shims.
