How far to travel with only 2 weeks vacation time/year

I would be curious to know the ages of some of the posters that say driving 200-250 mile a day is enough. I have driven to Gulf Shores, and Pensacola which is a little over 700 miles, in a day pulling the travel trailer and came home a week later. because being a younger family working man that is all of the vacation that I get. I feel that if you are comfortable driving 1000 miles a day go for it. I myself do not have any issues driving for 12 hours stopping only for gas, food, potty breaks.