Just finishing a trip through 7 western states and if towing, the max. limit varies state to state from 55 to 80 mph, plus the posted speed limits are constantly going up and down like a yo-yo. I set the C/C at 65 mph and never go above 65 regardless except the occasional time like after cresting a hill and it picks up 1 or 2 mph for a few seconds. I refuse to go above 65. If anyone has to go around us, that's just the way it is on the roads. I subscribe to the wisdom of a retired tire engineer on his rvtiresafety.com blog about max. speed on ST tires.
Someone posted above that GY Marathons are rated 75 mph. They are rated 65 but according to GY can run up to 75 ONLY if you add another 10 psi to the tires. I don't think that means you can do that 100 percent of the time. Rims would need to be rated for the higher pressure too. We have Marathons and I will not run them above 65 even with added pressure.
Have seen many FWs and TTs go flying past us on the highways. For some reason didn't see any to the side with a tire failure on this trip, but we've found that you just don't see many RVs using freeways or most highways because they're mostly on the slower & less hectic scenic routes. Have seen them with tire failures though on secondary highways in the past.
Besides max. speed, what most don't know is to never tow under-inflated or tow overloaded if using ST tires
What I don't like is that when you buy a new TT or FW, nobody tells the buyer about the max. speed rating of ST tires, load rating or to maintain the correct psi. Not the dealer or RV manufacturer and there's no sticker on the exterior sidewall.