These sort of questions get asked of me a lot. It may be because I used to sport a name tag that said "Navigator".
The simple and short answer is that there is only one complete and effective package available these days. That is Street Atlas. It can accommodate users between "knows what a mouse is" to "works largely by Lat/long and plans multi-thousand mile excursions". Buy it with the GPS puck and get a little inverter (if you don't have AC power underway) so you can let it run full time. You can pass the plan to a stand alone, or just load the critical points for the day's travel.
If you search up the
Discovery Owners site and collect the overlays for a bunch of good stuff.
Street Atlas still has some issues and the charts tend to be inaccurate and not up to date, so the brain must still be left engaged while traveling. It will tell pretty good routes most of the time and where to look to buy fuel and make and End Of Day plan.
Matt