If this discussion is about plugging versus patching a puncture when you're not on an RV trip ... then by all means take the tire to a shop and lhave them repair it the best way.
If this discussion is about plugging versus patching a puncture when in a campsite ... then probably installing - or having installed - your spare tire is best.
If this discussion is about plugging versus patching a puncture when out in the middle of nowhere where installing your spare can't or shouldn't be attempted by yourself in the remote spot where you're at ... then plugging is the way to go if you have a good enough compressor along and the power to run it.
I carry along in the RV a spare and the equipment to change it, a couple of truckers grade tire-inflation repair canisters, a truckers grade plugging kit, and a full pressure 120V compressor with a generator to power it.