I ran a test with my previous RV, then repeated it with my current RV, and got the same results.
I have a 1000 mile trip I take regularly. (Memphis to Colorado Springs to visit my sister.)
First RV: driving 70mph I got 6mpg, driving 60mph I got 9mpg (a 50% increase in gas mileage for a 14% decrease in speed). This was a 32' Class C on an E450 chassis.
Second RV: driving 70mph I got 8mpg, driving 60mph I got 12mpg (a 50% increase in gas mileage for a 14% decrease in speed). This is an Airstream travel trailer.
I assume that is almost entirely due to wind resistance.
So, my personal speed limit is 60ish. I say "ish" because most people drive on a 5mph division, 50 or 55 or 60. I like to drive at a slightly different speed so they don't "wolfpack" around me. I actually drive at 62mph. That way, everyone driving 60mph, I slowly pass. Everyone driving 65mph, slowly passes me. But, they don't bunch up around me.