The flow through are longer and stick out from the rim further.
I installed a set on my pickup. When I noticed how far they stuck out past the rim I was afraid I may drag them off if I were ever to get in deep mud or snow.
I sent them back for the standard sensor. Most of the time I have only had to make a pressure adjustment once year. With the TPMS there is no chance of loosing air to check pressures like can happen with a tire gauge.