Yup, it all boils down to what's in the truck and what shape the truck is in.
A good well maintained truck with a reasonable amount of stuff in it... No problem, but if you're one of those "no compromises" types that has to bring everything with them everywhere they go, it might get heavy and uncomfortable to drive.
That truck is 6 model years old now for all intents and purposes, could have hundreds of thousands of miles on it and be tired and beat because you couldn't keep your foot off the happy pedal with the 6.2L under the hood. Or it could be a nice low-mileage, well-cared-for machine.
Just you and your wife? Triplet 350lb linemen sons? Half a cord of firewood or a 1000cc quad in the bed?