Lots of people say the same thing Grit Dog, but life is not that simple.
There are always a lot more F250's to choose from on the lots, leading to overall better deals on price.
In my particular case, the fit in my garage is pretty tight, up top, that I have 1" of clearance to the garage door opener.
An F350 has 4" blocks on the back, so the back of the crew cab truck would hit the garage door opener. I've calculated the angles and measured both trucks' height with a tape measure.
In any case, back to the topic. A truck camper with a slide on an F250 would be pushing the axle weight rating, in my opinion, especially when loaded up for a trip.
I've looked at a lot of places, but I'm pretty sure it's the same axle as a SRW F350, but I don't have documentation on that.
Two E rated tires still limit you to 7280 lbs (2x3640 lbs Michelins) lbs on the rear axle. But the listed rear GAWR on my F250 with the truck camper package is is 6100 lbs, which is weird...
I would say it would be best not to load a heavy slider onto a SRW truck. You can do it, but it would be seriously pushing it according to
THIS.An F350 SRW would give you 6290 RAWR, an extra 190 lbs. Not exactly what I call a huge difference between having a 2 or a 3 in front of the 50.