It's a big block gasser. Mileage is going to s uck equally regardless of what slushbox is hooked to the back of it.
Only place you might pick up a smidge of gas mileage is haulin arse, bobtail, the 2nd OD of the 6 speed may give you a bit of a bump with a few less rpms, but at that speed you're burnin gas like it's free anyways.
Now, to get the Alli over the 4L80 whatever it is, is a big deal if you plan on keeping the truck. 5 or 6 speed. I would be more worried about the miles and condition of an old truck not whether it has the double OD.