I hate 4WD trucks and we live in the Great White North. Have never once needed it. If we get snow here on the west coast, which we we rarely do anymore, the truck just stays in the driveway. DW's Subaru will get us around if needed. Never needed 4WD anywhere with the TT either.
With 4WD, I don't like the fact they're up to 5-6" higher off the ground, there's more stuff to leak and need maintenance and you lose payload cap. Problem is, 2WD trucks are very hard to find unless you order a new one. The marketers have done a great job of convincing everyone you've gotta have 4WD.
OMG, our newly acquired 2012 Sierra 2500HD is so high off the ground, I can barely make it into the bed and almost need a stool and I'm not exactly short at 5'-8". It's higher than our old F250 and I thought that was bad enough.
I would think a lower center of gravity of 2WD would handle better.