My E-450 (V-10) requires 87 octane minimum, even at higher altitudes. So you might check to see what your manufacturer recommends, especially if your vehicle is still under warranty.
Though Ford also recommends 91 or higher while towing, but I've never put anything other than 87 in it.
Your vehicle is designed to operate on regular unleaded gasoline with a minimum pump (R+M)/2 octane rating of 87.
Some fuel stations, particularly those in high altitude areas, offer fuels posted as regular unleaded gasoline with an octane rating below 87. The use of these fuels could result in engine damage that will not be covered by the vehicle warranty.
For best overall vehicle and engine performance, premium fuel with an octane rating of 91 or higher is recommended. The performance gained by using premium fuel is most noticeable in hot weather as well as other conditions, for example when towing a trailer. See Towing .