I towed a fifth wheel with a 2005 Dodge; 3" lift and 35's. Zero issues, towed great. (yes the trailer was lifted too)
2011 Ram on 33" with a leveling kit we towed a travel trailer. Towed just fine. Front ball joints got sloppy around 40k miles, maybe accelerated by the big tires.
Those were diesels and the tire size did not impede towing at all. The 05 I thought actually towed better. IIRC it had 3.73 and on a grade if it dropped out of OD at highway speed it was screaming. With the 35's it dropped the revs down to where the direct drive rpm was much more palatable. At least at my towing speeds.
