My personnel experience with tuners in general was pretty negative. I got better mileage and more power with a Hyper Max Econ tuner right up to the point that the engine failed. Any increase in power is a result of increased cylinder pressures. You can keep increasing power until you find the weakest link in the engine and drive train. My experience so far has cost me $15,000 in engine repairs.
When the Big Three put an engine in a bigger towing rig, they detune it to make the engine last. The extra power is nice, but may result in engine or transmission failure down the road.