When loading up the front end, I pay attention to front GAVW. My 2013 3500HD spec is 4400 lbs - loaded up with camper, pax, winch & tray & such, it weighs in at 4340 - Thule carrier & 2-bikes (no winch of course), 4330#.
I keep a close eye on front tire air pressure @ 68-70psi (Michelin LXT LT265/70R18, rated 3285#) - I see no road handling or braking differences with the extra front weight ... brakes, suspension & tire wear @ 10k miles seem normal (service & rotate 3-4k) ... we'll see after another 10k ...