Experience towing w/ 2WD F250, 2500 or other 3/4 ton

This whole argument will be moot sooner or later, within the next 5-7 years if you ask me.

2WD trucks will go the way of the manual transmission. 4x4 is so overwhelmingly popular, and 2WD sales are dwindling year after year. Eventually the manufacturers will drop the 2WD option, and with it all the specialized components required to make them, thereby cutting production costs.