Many will slam the 6.0 just to have something to say. Yes I have an 04, put $4K into bullet proofing and it is a good truck. Now we dont try to move a 2 story house with it as we just dont have or want one, but we have a TT that we tow. Anyhow here is another point of view:
http://www.powerstroke.org/forum/general-6-0l-discussion/455490-dpm-money-ahead-6-0l-2.html
Read it, make the best guess decisions you can and then look at your options. on our last trip the 2 of us got about 13 mpg at 65 mph a friend with one of the 2 stories got about 10 and he was happy with his dodge as we traveled together. His truck runs ok, but when his wife rode with us for a while she was so happy to be able to think and hear herself talking without having to yell, yes he has a performance pipe for more power and noise. Mine is just a 4" gibson turbo back and very quiet. I have a hypertech econ tune he has nothing that I know of. He spent around a $1000 xmas before last when his fuel pump went out and he had to be towed so yes dodges fail also.
Anyhow, look at the article and then make your own decision.