I have an 07 Classic LBZ, lost #7 glow plug last year. Kinda shrugged my shoulders, I have 7 more, it'll start in the cold Alberta winters. And it did, no problem.
I do hate looking at the check engine light though. Took it to the dealer this past spring and they told me he same thing, replace all 8 for the small extra time and cost. Suppose I could do it myself but I'm tending to not turn my own wrenches any more.
Plugged my code reader in a month ago when it went into limp mode under a heavy haul, found that I now have #3 glow plug out as well. Now I'm down to 6. Still starts just fine, but winter is coming soon here. Suppose I should change them.
(Limp mode issue was not related to the glow plugs, it was a fuel pressure problem)
But in answer to your question, voice of experience here, I never noticed a difference with one bad plug. Will I with 2? Unknown. Maybe....
Might not get around to changing them. Work has been really bad and my income is way down from a few tears ago. We will see how it starts at minus 25.