I agree with the need to calculate your mileage over a long period of time. I also agree with the winter formula for gas, and I don't have a clue about diesel. I don't have a clue, not because I am a west coaster, I have no idea because I have never driven diesel pickups.
All that said, I do believe that aerodynamics plays a huge part in mileage. I towed a white box 21 ft trailer and got about 11-12 mpg. I traded for a 25 ft. Airstream that weighted 2000 pounds more and got the same mileage. Airstreams are one of the best when it comes to airflow around and behind their trailers.
The interesting observation came when, after owning this trailer for a few years, I added the bike rack to the back. Now, after a few more years with this setup, I am getting between 10 and 11 mpg. It doesn't matter if bikes are attached or not, the rack itself has impacted the turbulence at the back of the trailer.