How does this work?

We always unload if more than a night or two.

2017 Host Mammoth
2016 GMC Denali

I can't say I have ever seen a TC "unload" at any campground. Maybe if you were going to stay for a week or more.

TCs (that I know of) don't have a black water tank and some (most ? all?) have external gray water so about the only thing you have to disconnect is power and pack up any loose items before running on a side trip.

Thanks for all the info. My wife grew up cmaping in a truck camper, and therefore has no desire to revisit that option. LOL. I just think they're awesome, but I've never camped in one.

Depends what we’re doing and for how long.

Ours stays on the truck. If we are a few hours from home and staying a week or more my wife follows me with our SUV. If it is a longer distance from home and we are staying for a week or more in one place them we just rent a car. If we are traveling we just use the truck and camper for everything.

I leave mine on the truck. There is no place I would take the truck that the camper wouldn't fit. I just make sure I won't lose my camp site first. I also make sure I have all the food I need before setting up for the day.

Either way you want. If I was going to be at a camp site for a while and wanted to run to the store or an attraction on several different days I'd take it off. Also, when going to a lake I would often take it off so I could launch and retrieve the boat without the camper on.
I had power jacks with a wireless remote so I could take it on and off fairly quickly. If I had manual jacks with hand cranks it would have been different.
Mostly I left it on and we just drove the combination around like a motorhome.

when I owned one it stead on the truck. not hard to pack up and go.

Either way works. I like having the TC with me most of the time, so I can do lunch, etc.

There have been reports of some campgrounds that don’t allow you to take the TC off. In that case, I guess you bring it with you or book somewhere else.