is 2500 +/- each way road trip pratical in 10 days?

If you really want to know how far human body can go, pick up one of those log books for commercial drivers at any truck stop.
Somebody already made extensive research how much man can drive without endangering everybody around.
From what I remember they will allow driving 10hr for 5 days and then mandatory 2 days break.
If you consider doing that - you better make sure you get paid well.