I grew up with the Coleman catalytic heaters in the 50's-60's tent camping. The Mr Buddy heater came along after that was the greatest heater going then...
Then the more closed-up campers started to become popular and the Mr buddy heaters posed their biggest treat to life then. They are deemed safe if you follow all kinds of operations procedures.
I still use the Mr Buddy heater as a plan B back-up source of heat in my off-road POPUP setup but the heater has its perfect spot to sit which is on a high shelf arrangement right under an slightly opened fantastic ceiling fan. I also vent an additional window to allow fresh air to keep replacing the burned up oxygen hazard of the Mr Buddy heater. After doing all of this it just doesn't make sense using the Mr Buddy heater where you must open up outside vents letting alot of outside cold air coming into the trailer using this type of heater. The few times I have used the Mr Buddy heater was to heat up the inside as best we could then shut it down before we go to sleep. To me it just is NOT worth the risk to leave "ON" unattended all night.
I would go for a more permanent solution of mounting a vented CAT HEATER or use a hydronic type heater that uses hot water from the trailer water heater through a heat exchanger using low current fans blowing thru it. These unit work great for the smaller floorplan like the TC or smaller TT units.
This is the general idea of HYDRONIC TYPE heater setup.
These google photos show what this simple setup might look like
These google photos would be a perfect install idea for a vented CAT heater.. There was some recent conversations about the propane hose might get kinked feeding the CAT heater in this photo.
The idea of beefing up your battery bank is also a better idea to me then thinking along the line of using the Mr Buddy heater.
I would put some good thought before using a Mr Buddy type heater in a closed up trailer with alot of necessary precautions.
Roy Ken