I've run 3 sets of Maxxis tires on two different trailers, getting 25K or so miles/set before either tread wear (usually) or date came due for replacement. Did have one get a nail puncture, which the TPMS caught WELL before pressure dropped enough to result in tire failure. Other than that never any problems. But then the Towmax OEM tires on our Outback went 20K miles w/o any problems either.
The current sets on both my trailers are the Goodyear endurance. Endurance is one of the few ST tires with a >65mph speed rating w/o capacity derating, (85mph speed rating full rated load) and price wise were actually a few $$ less than Maxxis. Sof far I've only had the Goodyears for two years and one set has about 6K miles, the other 2K miles so can't verify reliability.