Any truck with that mileage, would need to have a real close look, IMHO. Whether or not it is a diesel or gasoline, most of the truck components are much the same.
About two years back I traded my 2002 Dodge Cummins in on the Chevy I drive now. The Cummins was still running fine but a lot of the Dodge stuff, was either very tired or I had already replaced them. The Dodge truck, like most brands, was fairly trouble free for the first 100K miles, but after that, up to the 144K miles I had on it when I traded it, it was just one thing after another. I put at least $6,000 in repairs into the truck those last 44K miles and it needed more to be spent on it. At about 100K the front end went all in the drain, needing new bearing clusters in front, new ball joints, tie rods, brakes, rotors, to the turn of over $3,000, the AC was a constant problem and expensive. But at least 90% of the time it was hauling our TC or pulling the 5th wheel. With the TC I was overloaded and probably the cause of many of the problems I had.
I would expect a 2010 model to have more like 30K miles on it, not over 100K. Think, based on my previous experiences, I would not consider a truck like that for use as a RV hauler. Would have been fine for ranch use, back when I was ranching in Oklahoma, but not to drive cross country. I know lots of forum members like to talk about the longevity of their diesel engines, and that is true for all of the diesels being used today. But there is a lot more to a truck than the engine. I had the 47RE transmission in my 2002 Dodge and it was getting ready to need an overhaul at about $4,500, plus needed a paint job, new interior. Just wasn't worth it to me to keep it.