With a motorized awning, we only extend it out when we are using it. I've seen way too many awning damaged/destroyed by quick powerful storms that pop up unexpectantly while people were out for the day. I also turn my water off when I'm going to be out for several hours, just in case a leak springs up.
When I park the TT on the side of my house, I extend the slide in order to load/unload, and then the slide gets put in after that. For the winter, I'll definitely have the slide in.
Based on my observations at CGs I visit, most seasonal renters leave their slides out all season. Some leave the slides out over the winter while others retract them.