I can't say on the truck as I've always run studs on my POV's but all the vehicles in our company fleet have always run Blizzak's including the cargo vans. Got them on 10 cars and 2 Sprinters now.
Nothing is worse in the snow than an empty Econoline but those Blizzaks made them seem like 4 wheel drive. With some weight in there they would climb mountains. We overloaded the van greatly and the tires had no problem.
I do recall that we had to special order them in the higher load ranges.
They do wear fast if the outside temp is to warm. Get them off early in the spring.