Our unit is rear kitchen and it works very well for us. The weight does not seem to be an issue as long as you don't hang a lot of additional weight on the bumper. Keeping an eye on your tongue weight is prudent in any set up. In your line of thinking wouldn't the kitchen on the right or left side put undue strain on that set of wheels and suspension?
I can understand Dutchmen's thinking about a rear living unit and the view that comes with such a set up so that leaves a front kitchen an option for you. As long as you have a tow vehicle that can handle a heavy tongue weight I would look at a front kitchen/rear living unit.
The most important thing in my opinion is a units livability and how it fits your needs. Find something that you will enjoy spending some time in and not just settle for "that'll do".
BTW, we have never had anything fall out of cupboards or any other such disasters with our rear kitchen. The only inconvenience I find is having the separate waste water take off at the rear and having to drag the hose to each take off. Its not that bad really but.....