Most parts of TCs “can” fail due to twisting offroad. My uncles pretty regularly bent their truck frames hauling hay.
That being said, if you are talking about simply going off pavement and are reasonable, I don’t think you will have an issue with many brands that are newer. Many of the early 2000 TCs had issues with slides either with the mechanism or the framing. How much of that was from how they were used ... who knows. I’ve had zero issues with mine, but I’ve read that at least one person had almost total destruction of one slide of the each same year/model of mine. YMMV.