With my 05 dmax, I got about 2 mpg less than a sw equal. Both had the same axel gearing, size etc. BUT, being as you add about 150 lbs in tires, this is about equal to adding 1500 lbs to a sw bed from an hp needed standpoint. ALong with another 200-300 lbs in fenders, extra springs, some cases ie ford at one time a .003" thicker frame for the dually, all add up to extra needed HP, which will chew up fuel mileage. This is equal to adding about a ton of wt to a single wheel as far as HP needed to get it going vs a SW.
If you go with GM, IIRC a newer rig with the 6.0 gas, a SW has a 10.5" RA vs possibly an 11.5" RA in the dually. Could be wrong on this, so a bit more hp moving wt, which again, takes about a 10-1 equal vs sitting there wt.
Lower mpg setups like a gas rig, will probably be closer to a gallon, but could be closer to 2 as with the diesels too.
Just my general experience with multiple dual vs single setups since 81.
Marty