My first TT I did not look into what the slide blocks. I was able to remove the hall door (not even sure why they had it) and then I could access the bathroom and bed areas. When I got my second, the one in the signature, I looked over every floor plan until I got one that I could have full access with the slide in.
For those that ask why? I stop on shoulders (on exit ramps)for those quick bathroom needs, grab for sandwiches, and even some rest areas that are not level or will not let you "camp" by having the slide out over night. I stop at truck stops to sleep, Walmart (un-level in some cases), many reasons why I stop and would not want to open the slide.