bobibyelm, another good post about being proactive with these trucks.
I do believe that a used truck with 100-150 thousand miles with the correct aftermarket modifications is more reliable than a brand new truck off the lot.
I say correct mods in that enough time elapsed for word to get out about what mods are effective for reliability and needs to be acted on. The truck forums are a great resource for this reason. A particular model therefore needs to have been around for a long enough period for the correct information to develop among it's owners.