We have had rear bath and mid-bath tts.
We prefer the mid-bath as the rear bath takes up what could be a lot of window room. In a rear bath, there are only windows on the side. In a mid bath, there are windows on both sides and rear. Typically, one backs into a space and the view - of a lake, ocean, mountains - is in the rear.
Another advantage of the mid bathroom is it separates the sleeping area from the living area. DH stays up late and I get up early. His noise at night doesn't keep me awake and my noise in the morning doesn't bother him. Also, he snores. If it is really bad, I can just escape to the living room and close the bedroom door. There is a larger 'buffer' area to muffle the sound.
We prefer the bathroom to be all in one rather than split. I like my sink and shower together; moving from room to room to get ready in the morning would be a pain. Having the doors block the access to the bedroom means the other person cannot access it when someone is showering or getting ready.
We never had a problem with smell with either bathroom. Both had ceiling vent fans with max-air covers and could be opened in the rain if necessary. Wait until after you flush before opening/turning on - it won't suck in the fumes from the black tank. We also used (powdered) laundry detergent each time we flushed the tank.
We now have a class A with a mid all in one bathroom and still really prefer that set up.
