Ol' Elvis, our former RV, had a split bath between the kitchen and bedroom. We loved the split design because one person didn't tie it all up at a given time - I could shower while my husband shaved. There was a door between the bedroom and the bathroom, and another between the bathroom and the kitchen, so it could be configured however you wanted it.
Our new TT has a rear bath. We like it because the extra weight is at the rear, to balance the weight on the hitch. Of course, our TT is just 22' long, so there's not much of a trek from one end to the other.
In the end, it's your preference, depending on how big the unit is and how you want to use it. I like both arrangements.
