I don't think you're "de-rating" your tires by running less pressure than the maximum. There's load charts available at the tire manufacturer's website most times that tells you what pressure to run depending on the weight each tire will carry.
This isn't the best idea for tires used in a trailer position as Roger Marble in rvtiresafety.com explains and other industry experts tell us.
Then along with ply shear and tread separations caused by derating the tire pressure to a minimum is the OP went with the Carlisle ST tires which require using max sidewaLL pressures to satisfy Carlisle tire warranty.
Carlisle says;
-Maintain air pressure at the maximum PSI recommended on the tire sidewall.
**The Warranty is void if the tire or wheel fails due to damage from improper inflation pressures, exceeding the maximum speed limit, or overloading the tire beyond the maximum load capacity stated on the sidewall**