I do not have a truck, but a MH and have traveled to Alaska several times.
MH has nearly 180,000 miles. We pull a toad.
As long as rig is in good shape won't have any problems.
I would ask what size fuel tank you have. Some of the smaller fueling places have disappeared over the years. There is a couple stratches of around 200 miles.
It is a great trip! Things have changed since I first went to Alaska in the '60s. Take your time!
Bud
USAF Retired
Pace Arrow
2003 Chev Ice Road Tracker